HALT-C Publications

  1. Shiffman ML, Di Bisceglie AM, Lindsay KL, Morishima C, Wright EC, Everson GT, Lok AS, Morgan TR, Bonkovsky HL, Lee WM, Dienstag JL, Ghany MG, Goodman ZD, Everhart JE. Peginterferon Alfa-2a and ribavirin in patients with chronic hepatitis C who have failed prior treatment. Gastroenterology. 2004 Apr;126(4):1015-23.

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  2. Morishima C, Chung M, Ng KW, Brambilla DJ, Gretch DR. Strengths and limitations of commercial tests for hepatitis C virus RNA quantification. J Clin Microbiol. 2004 Jan;42(1):421-5.
  3. Rothman AL, Morishima C, Bonkovsky HL, Polyak SJ, Ray R, Di Bisceglie AM, Lindsay KL, Malet PF, Chang M, Gretch DR, Sullivan DG, Bhan AK, Wright EC, Koziel MJ; HALT-C Trial Group. Associations among clinical, immunological, and viral quasispecies measurements in advanced chronic hepatitis C. Hepatology. 2005 Mar;41(3):617-25
  4. Lee WM, Dienstag JL, Lindsay KL, Lok AS, Bonkovsky, HL, Shiffman ML, Everson GT, Di Bisceglie AM, Morgan TR, Ghany MG, Morishima C, Wright ED, Everhart JE Evolution of the HALT-C Trial: pegylated interferon as maintenance therapy for chronic hepatitis C in previous interferon nonresponders Controlled Clinical Trials, Volume 25, Issue 5, October 2004, Pages 472-492
  5. Robert J. Fontana, Linas A. Bieliauskas, Carla Back-Madruga, Karen L. Lindsay, Ziad Kronfol, Anna S. Lok, Latha Padmanabhan, the HALT-C Trial Group Cognitive function in hepatitis C patients with advanced fibrosis enrolled in the HALT-C trial Journal of Hepatology. Volume 43, Issue 43 , October 2005, Pages 614-622
  6. Lok AS, Ghany MG, Goodman ZD, Wright EC, Everson GT, Sterling RK, Everhart JE, Lindsay KL, Bonkovsky HL, Di Bisceglie AM, Lee WM, Morgan TR, Dienstag JL, Morishima C. Predicting cirrhosis in patients with hepatitis C based on standard laboratory tests: Results of the HALT-C cohort. Hepatology. 2005 Aug;42(2):282-92.
  7. Adrian M. Di Bisceglie, Richard K. Sterling, Raymond T. Chung, James E. Everhart, Jules L. Dienstag, Herbert L. Bonkovsky, Elizabeth C. Wright, Gregory T. Everson, Karen L. Lindsay, Anna S.F. Lok, William M. Lee, Timothy R. Morgan, Marc G. Ghany, David R. Gretch and the HALT-C Trial Group Serum alpha-fetoprotein levels in patients with advanced hepatitis C: Results from the HALT-C Trial Journal of Hepatology. Volume 43, Issue 3 , September 2005, Pages 434-441.
  8. Bieliauskas LA, Back-Madruga C, Lindsay KL, Snow KK, Kronfol Z, Lok AS, Padmanabhan L, Fontana RJ, HALT-C Trial Group. Clinical Relevance of Cognitive Scores in Hepatitis C Patients with Advanced Fibrosis. Journal of Clinical and Experimental Neuropsychology, Volume 28, Number 8 / Nov 2006, Pages 1346 - 1361.
  9. Polyak SJ, Sullivan DG, Austin MA, Dai JY, Shuhart MC, Lindsay KL, Bonkovsky HL, Di Bisceglie AM, Lee WM, Morishima C, Gretch DR Comparison of amplification enzymes for Hepatitis C Virus quasispecies analysis Virol J. 2005 Apr 22;2(1):41
  10. Sanyal AJ, Fontana RJ, Di Bisceglie AM, Everhart JE, Doherty MC, Everson GT, Donovan JA, Malet PF, Mehta S, Sheikh MY, Reid AE, Ghany MG, Gretch DR, The HALT-C Trial Group. The Prevalence and Risk Factors Associated with Esophageal Varices in Subjects with Hepatitis C and Advanced Fibrosis. GI Endoscopy, 2006 Dec; 64(6):855-864.
  11. Morishima C, Polyak SJ, Ray R, Doherty MC, Di Bisceglie AM, Malet PF, Bonkovsky HL, Sullivan DG, Gretch DR, Rothman AL, Koziel MJ, Lindsay KL, and the Hepatitis C Antiviral Long-Term Treatment against Cirrhosis Trial Group. Hepatitis C Virus-Specific Immune Responses and Quasi-Species Variability at Baseline Are Associated with Nonresponse to Antiviral Therapy during Advanced Hepatitis C. J Infect Dis, 2006 Apr;193(7):931-40.
  12. Fontana RJ, Sanyal AJ, Mehta S, Doherty MC, Neuschwander-Tetri BA, Everson GT, Kahn JA, Malet PF, Sheikh MY, Chung RT, Ghany MG, Gretch DR; the HALT-C Trial Group. Portal Hypertensive Gastropathy in Chronic Hepatitis C Patients with Bridging Fibrosis and Compensated Cirrhosis: Results from the HALT-C Trial. Am J Gastroenterol. 2006 Mar 30
  13. Lok ASF, Everhart JE, Chung RT, Padmanabhan L, Greenson JK, Shiffman ML, Everson GT, Lindsay KL, Bonkovsky HL, Di Bisceglie AM, Lee WM, Morgan TR, Ghany MG, Morishima C, HALT-C Trial Group. Hepatic steatosis in hepatitis C: Comparison of diabetic and nondiabetic patients in the hepatitis C antiviral long-term treatment against cirrhosis trial. Clin Gastroenterol Hepatol. 2007 Feb; 5(2) 245-54.
  14. Bonkovsky HL, Snow KK, Malet PF, Back-Madruga C, Fontana RJ, Sterling RK, Kulig CC, Di Bisceglie AM, Morgan TR, Dienstag JL, Ghany MG, Gretch DR, HALT-C Trial Group. Health-related quality of life in patients with chronic hepatitis C and advanced fibrosis. J Hepatol. 2007 Mar; 46(3):420-31. Epub 2006 Nov
  15. Lindsay KL, Morishima C, Wright EC, Dienstag JL, Shiffman ML, Everson GT, Lok AS, Bonkovsky HL, Lee WM, Morgan TR, Ghany MG; HALT-C Trial. Blunted cytopenias and weight loss: new correlates of virologic null response to re-treatment of chronic hepatitis C.Clin Gastroenterol Hepatol. 2008 Feb;6(2):234-41.
  16. Morishima C, Morgan TR, Everhart JE, Wright EC, Shiffman ML, Everson GT, Lindsay KL, Lok ASF, Bonkovsky HL, Di Bisceglie AM, Lee WM, Dienstag JL, Ghany MG, Gretch DR, and the HALT-C Trial Group. HCV RNA Detection by TMA During the Hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial. Hepatology 2005; 44: 360-367.
  17. Bonkovsky HL, Naishadham D, Lambrecht RW, Chung RT, Hoefs JC, Nash SR, Rogers TE, Banner BF, Sterling RK, Donovan JA, Fontana RJ, Di Bisceglie AM, Ghany MG, Morishima C, and the HALT-C Trial Group. Influence of Iron and HFE Mutations on Severity and Response to Therapy during Retreatment of Advanced Chronic Hepatitis C in the HALT-C Trial. Gastroenterology 2006; 131: 1440-1451.
  18. Everson GT, Shiffman ML, Morgan TR, Hoefs JC, Sterling RK, Wagner DA, Kulig CC, Curto TM, Wright EC, HALT-C Trial Group. The spectrum of hepatic functional impairment in compensated chronic hepatitis C: results from the HALT-C trial. Aliment Pharmacol Ther. 2008 May; 27(9): 798-809.
  19. Everson GT, Hoefs JC, Seeff LB, Bonkovsky HL, Naishadham D, Shiffman ML, Kahn JA, Lok ASF, Di Bisceglie AM, Lee WM, Dienstag JL, Ghany MG, Morishima C, and the HALT-C Trial Group. Impact of Disease Severity on Outcome of Antiviral Therapy for Chronic Hepatitis C: Lessons from the HALT-C Trial. Hepatology 2006 Dec; 44(6):1675-92.
  20. Shiffman ML, Ghany MG, Morgan TR, Wright EC, Everson GT, Lindsay KL, Lok ASF, Bonkovsky HL, Di Bisceglie AM, Lee WM, Dienstag JL, Gretch DR, and the HALT-C Trial Group. Impact of Reducing Peginterferon Alfa-2a and Ribavirin Dose During Retreatment in Patients With Chronic Hepatitis C. Gastroenterology, 2007 Jan; 132(1):103-12.
  21. Bieliauskas LA, Back-Madruga C, Lindsay KL, Wright EC, Kronfol Z, Lok ASF, Fontana RJ, HALT-C Trial Group. Cognitive reserve and neuropsychological functioning in patients infected with hepatitis C. Journal of the International Neuropsychological Society, 2007 13: 1-6.
  22. Fontana RJ, Bieliauskas LA, Lindsay KL, Back-Madruga C, Wright EC, Snow KK, Lok ASF, Kronfol Z, Padmanabhan L, HALT-C Trial Group. Cognitive function does not worsen during pegylated interferon and ribavirin retreatment of chronic hepatitis C. Hepatology. 2007 May;45(5):1154-63.
  23. Everson GT, Martucci MA, Shiffman ML, Sterling RK, Morgan TR, Hoefs JC, The HALT-C Trial Group. Portal-systemic shunting in patients with fibrosis or cirrhosis due to chronic hepatitis C: the minimal model for measuring cholate shunt clearances and shunt. Alimentary Pharmacology & Therapeutics. 2007 Aug 1;26(3):401-10.
  24. Fontana RJ, Goodman ZD, Dienstag JL, Bonkovsky HL, Naishadham D, Sterling RK, Su GL, Ghosh M, Wright EC; HALT-C Trial Group. Relationship of serum fibrosis markers with liver fibrosis stage and collagen content in patients with advanced chronic hepatitis C. Hepatology. 2008 Jan 3;47(3):789-798.
  25. Seeff LB, Curto TM, Szabo G, Everson GT, Bonkovsky HL, Dienstag JL, Shiffman ML, Lindsay KL, Lok AS, Di Bisceglie AM, Lee WM, Ghany MG; HALT-C Trial Group. Herbal product use by persons enrolled in the hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial. Hepatology. 2008 Feb;47(2):605-12.