Epidermal growth factor gene functional polymorphism and the risk of hepatocellular carcinoma in the HALT-C cohort

Investigators:

Ray Chung , Barham Abu Dayyeh, Jules Dienstag, Kenneth K. Tanabe, Tom O'Brien

Hypotheses/Aims

HALT-C subjects with the EGF G/G or G/A genotypes will have increased odds for developing HCC after controlling for age, sex, ethnicity, and the severity of liver disease by histopathology. Also, they will have higher serum levels of EGF.